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29 July, 2010
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17 August, 2010
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08 September, 2010
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09 September, 2010
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30 August, 2010
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23 September, 2010
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Killing Pain with Killer Snails:
The Development of the Analgesic, Prialt®
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qed@qb3 - UCSF
Thursday, September 3, 2009 12:00 to 1:00 pm Byers Hall Room 212 |
| Ziconotide is the first intraspinal analgesic approved in the U.S. (2004) for the management of severe chronic pain in more than two decades. Ziconotide, the synthetic equivalent of a 25 amino acid neuroactive peptide originally isolated from the magician's cone snail, is a potent, selective blocker of neuronal N-type voltage-gated calcium channels that mediate the propagation and processing of noxious stimuli by pain pathway neurons. Ziconotide has its own unique safety issues, but as a non-opiate analgesic, it does not suffer from many of the limitations of opiate analgesics. The safety and efficacy of ziconotide have been well documented in several clinical trials and, subsequently, through the experience of thousands of additional pain patients. The history of the development and commercialization, as well as speculations on future uses of Ziconotide, will be discussed. |
Lunch provided, but space is limited so please reserve a seat at http://www.acteva.com/booking.cfm?bevaID=175891 |
| This email was sent to morgan@luminogenics.com by douglas.crawford@ucsf.edu | |
| QB3 | 1700 4th Street | Suite 214 | San Francisco | CA | 94158 | |